This Request for Information (RFI) and Request for Proposal (RFP) process invites kidney microphysiological systems (MPS) developers to apply to partner with IQ MPS to conduct a study assessing the ability of kidney MPS to predict drug-induced renal proximal tubule injury and replicate human-relevant safety biomarker profiles by comparing in vitro results with in vivo data (human, rat, dog, and NHP).

This scientific engagement series provides a forum for developers and providers of complex in vitro models (CIVMs) to present technologies and receive direct feedback from IQ MPS member companies on qualification, reproducibility, and application in drug development.

This project will evaluate kidney microphysiological system (MPS) platforms for their ability to predict clinically relevant toxicological responses and ADME properties, with the goal of assessing their readiness for fit-for-purpose applications in drug discovery and development.

This project will evaluate gastrointestinal (GI) microphysiological system (MPS) platforms for their ability to predict clinically relevant toxicological responses and ADME properties, with the goal of assessing their readiness for fit-for-purpose applications in drug discovery and development.