IQ MPS
IQ Microphysiological Systems Affiliate
An Affiliate of the International Consortium for Innovation and Quality in Drug Development
Publications
IQ MPS develops and publishes manuscripts with the purpose of outlining the contemporary pharmaceutical industry perspective and considerations for developing, evaluating, and characterizing MPS models to support drug discovery and development.
IQ MPS Manuscripts Series 2.0
IQ MPS manuscripts published in Altex are available as a special edition of the Journal.
Introduction
Under Development
Oligonucleotides
Ramsden, D., Belair, D. G., Agarwal, S., Andersson, P., Humphreys, S., Dalmas, D. A., ... & Cichocki, J. A. (2022) "Leveraging microphysiological systems to address challenges encountered during development of oligonucleotide therapeutics". ALTEX-Alternatives to animal experimentation. Available here.
Immune Systems
Wang, X., Kopec, A., Collinge, M., David, R., Grant, C., Hardwick, R., Navratil, A., Patel, N., Rowan, W. and Marshall, N. (2022) “Application of Immunocompetent Microphysiological Systems in Drug Development: Current Perspective and Recommendations”, ALTEX - Alternatives to animal experimentation. Available here.
Disease Models
Irrechukwu, O., Yeager, R., David, R. ., Ekert, J., Saravanakumar, A. and Choi, C. K. (2023) “Applications of microphysiological systems to disease models in the biopharmaceutical industry: Opportunities and challenges”, ALTEX - Alternatives to animal experimentation.. Available here.
Ocular
Under Development
Reproductive
Under Development
BBB
Under Development
Gene Editing
Under Development
Cell Therapies
Under Development