Publications

IQ MPS develops and publishes manuscripts with the purpose of outlining the contemporary pharmaceutical industry perspective and considerations for developing, evaluating, and characterizing MPS models to support drug discovery and development.

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IQ MPS Manuscripts Series 2.0
IQ MPS manuscripts published in Altex are available as a special edition of the Journal.

Introduction

Under Development

Oligonucleotides

Ramsden, D., Belair, D. G., Agarwal, S., Andersson, P., Humphreys, S., Dalmas, D. A., ... & Cichocki, J. A. (2021). Leveraging microphysiological systems to address challenges encountered during development of oligonucleotide therapeutics. ALTEX-Alternatives to animal experimentation. Available here.

Immune Systems

Wang, X., Kopec, A., Collinge, M., David, R., Grant, C., Hardwick, R., Navratil, A., Patel, N., Rowan, W. and Marshall, N. (2022) “Application of Immunocompetent Microphysiological Systems in Drug Development: Current Perspective and Recommendations”, ALTEX - Alternatives to animal experimentation. Available here.

Disease Models

Under Development

Ocular

Under Development

Reproductive

Under Development

CNS/Peripheral

Under Development

CNS/BBB

Under Development

Gene Editing

Under Development

Cell Therapies

Under Development

Read the MPS Affiliate's Manuscript 1.0 Series Here