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IQ MPS develops and publishes manuscripts with the purpose of outlining the contemporary pharmaceutical industry perspective and considerations for developing, evaluating, and characterizing MPS models to support drug discovery and development.


IQ MPS Manuscripts Series 2.0
IQ MPS manuscripts published in Altex are available as a special edition of the Journal.


Under Development


Ramsden, D., Belair, D. G., Agarwal, S., Andersson, P., Humphreys, S., Dalmas, D. A., ... & Cichocki, J. A. (2022) "Leveraging microphysiological systems to address challenges encountered during development of oligonucleotide therapeutics". ALTEX-Alternatives to animal experimentation. Available here.

Immune Systems

Wang, X., Kopec, A., Collinge, M., David, R., Grant, C., Hardwick, R., Navratil, A., Patel, N., Rowan, W. and Marshall, N. (2022) “Application of Immunocompetent Microphysiological Systems in Drug Development: Current Perspective and Recommendations”, ALTEX - Alternatives to animal experimentation. Available here.

Disease Models

Irrechukwu, O., Yeager, R., David, R. ., Ekert, J., Saravanakumar, A. and Choi, C. K. (2023) “Applications of microphysiological systems to disease models in the biopharmaceutical industry: Opportunities and challenges”, ALTEX - Alternatives to animal experimentation.. Available here


Under Development


Under Development


Under Development

Gene Editing

Under Development

Cell Therapies

Under Development

Read the MPS Affiliate's Manuscript 1.0 Series Here

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